New Objective PicoFrit® Columns

PicoFrit® Columns

• Eliminates band broadening
• Sprays directly from column to inlet
• Minimizes post-column loss
• Integral frit greatly reduces tip clogging
• Robust performance compatible with automated systems
• High-resolution separations yield femtomole sensitivity

The PicoFrit Advantage

PicoFrit™ Column Standard Column Coupled with a Tip

Spraying directly off the column boosts the performance of your mass spectrometer compared to that provided by a column attached to a tip. Less time spent making connections increases efficiency. That's the PicoFrit advantage.

• Ion chromatograms for full-scan MS data of 4 angiotensin variants at 25 fmol injected on column
• The chromatogram at left was obtained using a C18-packed column coupled to a coated emitter with a union
• The chromatogram at right was obtained using a C18-packed PicoFrit column (75 µm OD/15 µm ID)
• The PicoFrit column yielded better peak shape with decreased peak width, resulting in higher sensitivity

PicoFrit Specifications:

• Column IDs 75 µm and 50 µm, tip IDs 15 µm and 10 µm
• Packed with a variety of high-performance, reverse-phase, HPLC packings
• Short columns (1 cm) for sample concentration/desalting procedures
• Medium columns (5 cm) for rapid-gradient LC-MS
• Long columns (>10 cm) for gradient LC-MS
• Biphasic columns for shotgun digests

UHPLC Performance in a PicoFrit™ Package
PicoFrit columns are the perfect format for fast-gradient chro- matography. Packed with any of our sub-3 µm particle sorbents, PicoFrit columns deliver ultra-high-performance results.

PicoFrit Chemistries

Use the Media Code indicated in place of the XXXX in the part number when ordering pre-packed columns. Our selection of availablechemistries is always changing. If you require a media that is not noted below, please contact us for availability, or for information oncustom column packing to your specification and with your supplied media. Please note: New Objective does not provide bulk material.Substitute the desired tip size where ## appears in any Part Number.

New Objective Chemistries