
by O. David Sparkman
Global View Publishing, June 2006, 198 pages. ISBN-10: 0966081390, ISBN-13: 9780966081398.
This book has been listed as a source of appropriate terminology in the instructions to Authors section of the Journal of the American Society of Mass Spectrometry since the book's publication in 2000.
Whether you are a newcomer, teacher, manager, or experienced practitioner engaged in mass spectrometry, you will find this handy desk reference an invaluable tool for improving your results.
"The Mass Spec Desk Reference is a great resource for every facet of our laboratory. It is a handbook, reference resource, and textbook; all in one. Its vapor pressure was so high that we had to buy everyone a copy."
-- Dr. Steven Colby, Patent Attorney, San Jose, California
"I am pleased to recommend and comment on this publication by my longtime friend and colleague... The Mass Spec Desk Reference gives an excellent overview to, as well as specific details on, the language and scientific communication media used in the active world of mass spectrometry."
-- Dr. J. Throck Watson, Professor, Michigan State University
Author: David Sparkman is a highly acclaimed instructor for a number of ACS (American Chemical Society) short courses on mass spectrometry; including GC/MS, LC/MS, and interpretation. He has engaged in these activities for over thirty years; in the process he has compiled this survival guide.
Much of the book is in a dictionary format of terms marked correct or incorrect along with a description and comments. Some examples follow:
(p. 55) Correct:
resolving power -- the term used to define the ability of a mass spectrometer to separate ions of two different m/z values. The resolving power of the mass spectrometer is defined as M/ΔM where M is the m/z value of a single-charge ion, and ΔM is the difference between M and the value of the next highest m/z value ion that can be distinguished (separated) from M in m/z units. Resolving power is determined from the measurement of mass spectral peaks and should be reported with the method by which ΔM was determined (i.e., full width at half-maximum height [FWHM], 10% valley [two adjacent mass spectral peaks of equal height overlap so that the height from the baseline to the top of the overlap valley is 10%] method, 50% valley method, etc.). The FWHM results in a value for resolving power that is twice that obtained with the 10% valley method. It should be noted that using the mass spectral peak width at 5% of its full height is considered to be equivalent to the 10% valley method as illustrated in Figure 10.
(p. 53) Incorrect:
protonated molecular ion -- when used to describe a molecule that has been protonated. This term implies that the molecular ion (a positive-charge species) has reacted with a proton (another positive charge species). For this reaction to happen, the two species would have to come in contact with one another. This event is unlikely because charges repel one another.
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