Tal-Aviv Isotope Abundance Analysis (IAA)

Summary

Documentation:

The Tal-Aviv Isotope abundance analysis (IAA) software provides a novel method for sample identification based on isotope abundance analysis (IAA). Our IAA software automatically inverts the isotope abundance information in experimentally obtained MS spectra into elemental formula information. More importantly, our IAA software, among other things, links with the NIST MS library and automatically confirms or rejects its identification. In case of a confirmation, the sample identification is unambiguous since the confirmation is done by an independent set of data and method. In the case of a rejection (such as when the compound is not included in the library or due to matrix interference), the IAA software independently provides a list of elemental formulas with declining order of matching to the experimental data, in similarity to costly accurate mass measurements. The Tal-Aviv IAA software can further help with sample identification through IAA of major high mass fragments, it provides unique information on the presence or lack-of certain elements and can help with isotope enrichment experiments. IAA is ideally applicable to GC-MS with supersonic molecular beams (SMB) since it benefits from having a trustworthy and high abundance true molecular ion. However, the Tal-Aviv IAA software is also highly useful in combination with standard quadrupole based GC-MS such as the Agilent 5972/3/5 and it can give you the highest confidence level in the identification of your sample compounds. It is as good as it gets in sample identification and you can easily evaluate it NOW on your available Agilent GC-MS files.

In comparison with accurate mass alternatives the Tal-Aviv IAA software possesses the following major advantages:

A) Linked with the NIST library, which is the industry standard identification method. Thus, the combination of IAA with NIST (IAA-NIST) significantly improves the identification confidence level using IAA information to uniquely confirm or reject the library identification results.
B) IAA-NIST identification probability is much higher than that of accurate mass alternatives for compounds that are in the library database.
C) IAA-NIST identification process results in sample molecule identification with its true chemical names and not just elemental formulas.
D) IAA-NIST uniquely provides isomer identification from MS fragments, while the IAA increases the probability of a correct elemental formula of that isomer. None of the available accurate mass methods and systems provide any isomer information.
E) No need to use frequent or on-line mass tune.
F) Operates with standard centroid mode (does not require data collection in profile mode, which generates x10 bigger files). Consequently the Tal-Aviv IAA software can be used to analyze old files that you have already acquired.
G) Far less expensive than any available accurate mass alternative.

Demo and Additional Information

For further information on IAA please read - Tal Alon and Aviv Amirav "Isotope Abundance Analysis Method and Software for Improved Sample Identification with the Supersonic GC-MS” Rapid Commun. Mass Spectrom. 20, 2579-2588 (2006). You may ask us for this paper and we shall email it to you as a pdf file. Furthermore, we can email you the Tal-Aviv IAA software manual upon your request for having closer information on the various software features. We shall be happy to explore together the utilization and applicability of the Tal-Aviv IAA software of Aviv Analytical for your analysis and sample compounds. Please email us your ChemStation chromatogram file and we shall email you back our IAA analysis results. We trust that you will find the Tal-Aviv IAA software as easy to use and as the best tool for improving your sample identification. Thus, we are willing to give it for 30 days free trial following our communication and your purchase order so that if for any reason you do not like it you do not pay for it.

Below is the front screen of the Tal-Aviv IAA software.

Short video:

Ordering

Part No.	Description	UOM	est wt.	Quantity In Stock	Price
IAA	Tal Aviv IAA Software	EA	0	0^{[*L]Standard lead-time for out-of-stock items is approximately two weeks depending on the item.}	$4900.00
[*L] Standard lead-time for out-of-stock items is approximately two weeks depending on the item.
Ordering information. International (non-US) prices available through your local dealer.

The Tal-Aviv IAA method and software is protected by US patent # 7345275 of Tal Alon and Aviv Amirav.

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